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Encyclopedia of Custom Chemical Manufacturing
Welcome to Informex365.com, the new online portal for the custom chemical manufacturing marketplace. Informex365.com is a search engine-optimized directory of suppliers for approximately 200 process chemical reactions and allied service listings commonly used within the chemical, pharmaceutical, and biotech industries. This site is an online extension of the InformexUSA show, the essential annual event for sophisticated chemistry, which brings together a comprehensive global network of qualified buyers and sellers of fine, specialty and custom chemicals.

Informex365.com is structured not only to be an online buyer’s guide for process chemical reactions, but also to provide a year-round forum for additional company features and fine chemical market information such as technical papers, audio/visual presentations, news, etc.
 
What's New
Bringing biocatalysis into the mainstream
Biocatalysis has the potential to bring lasting beneficial changes to the chemical industry. The authors ask (and answer) the question: Given the benefits of biocatalysis, why has its impact on chemic...
Supporting research into new anti-viral technologies
Retroscreen Virology Limited is a leading company in anti-viral research, clinical trials and experimental challenge studies and, amongst other projects, is developing an intranasal vaccine against av...
Cell encapsulation gives consistent cell assay results
Q Chip has developed a microfluidic-based cell encapsulation system that produces uniform capsules under sterile and enclosed conditions. Encapsulation offers a number of advantages for cell-based ass...
Chiral chromatography in API synthesis: why, when, where and how?
Preparative chiral chromatography continues to gain popularity in the development and commercial production of APIs synthesised as pure enantiomers. However, the benefits of this technique are still n...
Teva to acquire Barr Pharmaceuticals
Teva Pharmaceutical Industries Ltd and Barr Pharmaceuticals, Inc have signed a definitive agreement under which Teva will acquire Barr, the fourth-largest generic drug company worldwide. Teva says the...
Custom reactor system from Syrris
Chemistry automation product innovator Syrris is now offering custom laboratory reactor systems from 10ml to 100 litres. Designed and built to the customer’s specification, complete systems including ...
Rentschler expands biotech site and sells pharma business
Rentschler is investing a further €14 million in its expansion of the Rentschler Biotechnologie GmbH site in Laupheim, Germany following the recent €50 million investment in biotechnological developme...
New process development workstation from Radleys
The new Storm™ Workstation from Radleys provides precisely controlled heating and cooling from -65 to +200ºC when used with a suitable circulator.
Minakem subsidiary PennAkem acquires Penn Specialty Chemicals
Penn Specialty Chemicals, Inc has been acquired by PennAkem, a wholly-owned subsidiary of the French Minakem Group. Based in Memphis, Tennessee, USA with production facilities in the USA and China, Pe...
NIH extends agreement with BioFocus DPI
The US National Institutes of Health (NIH) has extended an agreement with Galapagos’ service division BioFocus DPI for the operation of the Molecular Libraries Small Molecule Repository (MLSMR) until ...
MediGene exercises option for anti-cancer monoclonal antibodies
MediGene AG is to exercise an option granted two years ago by the German Cancer Research Center (DKFZ) for the development and commercialisation of an antibody for the treatment of different types of ...
Lonza closes amaxa acquisition
Lonza Group has completed its acquisition of amaxa in line with its strategy of growing its life-science platform. amaxa is a supplier to the cell discovery market with proprietary technologies in tra...
Lilly to acquire SGX Pharmaceuticals
Eli Lilly and Company and SGX Pharmaceuticals, Inc have signed a definitive merger agreement providing for the acquisition of SGX in an all-cash transaction. SGX, based in San Diego, California, USA, ...
Kinaxo Biotechnologies awarded grant for chemical proteomics expansion
Kinaxo Biotechnologies GmbH has been awarded a €575,000 grant by the Bavarian Ministry of Economic Affairs, Infrastructure, Transport and Technology to help expand the applications for its chemical p...
KeyNeurotek Pharmaceuticals reports breakthrough discovery in Huntington's disease
KeyNeurotek Pharmaceuticals AG, a biotechnology company focused on the development and marketing of drugs against autoimmune diseases and degenerative disorders of the central nervous system, has anno...
ISOCHEM and Nycomed renew drug API contract
ISOCHEM and Nycomed have signed a contract renewing for the second time their contract initially signed in 1999 for the supply of Pantoprazole, the active ingredient of Nycomed’s gastrointestinal drug...
innovatis introduces multi-mode cell imaging system
innovatis Inc has introduced Cellavista, an image-based system that can be used for rapid visualisation of a broad range of cellular assays, while performing image analysis simultaneously. Combining b...
Genzyme Corporation and PTC Therapeutics collaborate on genetic diseases treatment
Genzyme Corporation and PTC Therapeutics, Inc have formed an exclusive global collaboration to develop and commercialise PTC124, PTC’s novel oral therapy in late-stage development for the treatment of...
FDA approves chorea drug
The FDA has approved Xenazine (tetrabenazine) for the treatment of chorea in people with Huntington’s disease. Chorea is the jerky, involuntary movement that occurs in people with this disease. Xenazi...
EFCG launches Voluntary Guidelines for fine chemical manufacturers
The European Fine Chemicals Group (EFCG) has launched its Voluntary Guidelines for ISO-regulated Fine Chemical Manufacturers. The Voluntary Guidelines were originally developed by the Agrochemical Int...
Diatos commences Phase II clinical trials in prostate and breast cancer
Diatos SA, a biopharmaceutical company focusing on the research, development and commercialisation of targeted anti-cancer drugs, has commenced Phase II clinical trials for DTS-201, a peptidic prodrug...
Sample preparation system for automated real-time flow cytometry
Copley Scientific has introduced the new MSP Model 5000 FlowCytoPrep Sample Preparation System (5000 FCP SPS), a biological sample preparation system that automates the time-consuming manual steps of ...
Charles River opens new research facility
Charles River Laboratories International, Inc has opened a new 52,000 square foot facility in Frederick, Maryland, USA where it will work with the National Cancer Institute to produce new research mod...
Cefic launches SIEFreach chemical registration service
Cefic and five national chemical associations have launched a service that will facilitate and ease the exchange of information between companies with the final goal of submitting the registration dos...
BASF scientist wins Siegfried Medal
BASF biocatalysis researcher Professor Dr Klaus Ditrich is to receive the Siegfried Medal for his work in process chemistry. The prize is awarded every other year by Swiss company Siegfried Ltd in coo...
Aquapharm and Dr. Reddy’s complete licence agreements
Scottish marine biotechnology company Aquapharm Biodiscovery Limited has signed a new commercial licence agreement and an extension of an existing research and development licence agreement with Dr. R...
AMRI expands Singapore lab facilities
AMRI has opened its first in vitro biology laboratory in Singapore and has completed a 10,000 sq ft laboratory expansion for medicinal chemistry discovery services, thereby more than doubling the capa...
Alsace BioValley in €11 million life sciences building project
Alsace BioValley has announced the construction of a new building dedicated to life sciences and housing a Center for Integrative Biology as well as a Platform Center serving research and industry. Th...
More What's New >>
Encyclopedia of Custom Chemical Manufacturing
Sulfoxidation
A sulfoxide is a chemical compound containing a sulfinyl functional group attached to two carbon atoms. Sulfoxides can be considered as oxidized sulfides. (The use of the alternative spelling sulphoxi...
Sonogashira coupling
In organic chemistry, a Sonogashira coupling is a coupling reaction of terminal alkynes with aryl or vinyl halides. This reaction was first reported by Kenkichi Sonogashira and Nobue Hagihara in 1975.
Scale-up, Custom Chemical
Organic synthesis is a special branch of chemical synthesis and is concerned with the construction of organic compounds via organic reactions. Organic molecules can often contain a higher level of com...
Radioisotopic Labeling
Isotopic labeling is a technique for tracking the passage of a sample of substance through a system. The substance is 'labeled' by including unusual isotopes in its chemical composition. If these unus...
Pharmaceutical Intermediate Manufacturing
A reaction intermediate or an intermediate is a molecular entity that is formed from the reactants (or preceding intermediates) and reacts further to give the directly observed products of a chemical ...
Oxo reactions
In chemistry oxo, the formal IUPAC nomenclature for a ketone functional group. However, other prefixes are also used by various books and journals. For some common chemicals (mainly in biochemistry)...
Optical resolution
Optical resolution describes the ability of an imaging system to resolve detail in the object that is being imaged.
Mitsunobu reaction
The Mitsunobu reaction is an organic reaction that converts an alcohol into a variety of functional groups, such as an ester, using triphenylphosphine and diethyl azodicarboxylate (DEAD). Of importanc...
Low Temperature Reactions
In physics or engineering, cryogenics is the study of the production of very low temperatures (below –150 °C, –238 °F or 123 K) and the behavior of materials at those temperatures. Rather than the fam...
Ionic liquids
An ionic liquid is important a liquid that contains essentially only ions. Some ionic liquids, such as ethylammonium nitrate are in a dynamic equilibrium where at any time more than 99.99% of the liqu...
Hydrogen Fluoride reactions
Hydrogen fluoride is a chemical compound with the formula HF. Together with hydrofluoric acid, it is the principal industrial source of fluorine and hence the precursor to many important compounds inc...
Gomberg-Bachmann reaction
The Gomberg-Bachmann reaction, named for the Ukrainian-American chemist Moses Gomberg and the American chemist Werner Emmanuel Bachmann, is an aryl - aryl coupling reaction via a diazonium salt.
Fermentation Reactions, Chemical
Fermentation is the process of deriving energy from the oxidation of organic compounds, such as carbohydrates, using an endogenous electron acceptor, which is usually an organic compound. This is in c...
Distillation Services, Chemical
Distillation is a method of separating chemical substances based on differences in their volatilities in a boiling liquid mixture. Distillation usually forms part of a larger chemical process, and is ...
Dehydrogenation
Dehydrogenation is a chemical reaction that involves the elimination of hydrogen (H2). It is the reverse process of hydrogenation. Dehydrogenation reactions may be either large scale industrial proces...
Custom Chemical Manufacturing,Synthesis
In chemistry, chemical synthesis is purposeful execution of chemical reactions in order to get a product, or several products. This happens by physical and chemical manipulations usually involving one...
Contract Research Service
A Contract Research Organization (CRO) is an organization that offers clients a wide range of pharmaceutical research services. In the Code of Federal Regulations (CFR), the U.S. Food and Drug Adminis...
Condensation Reactions
A condensation reaction is a chemical reaction in which two molecules or moieties (functional groups) combine to form one single molecule, together with the loss of a small molecule. When this small m...
Carboxylation
Carboxylation in chemistry is a chemical reaction in which a carboxylic acid group is introduced in a substrate. The opposite reaction is decarboxylation.
Birch reduction
The Birch reduction is the organic reduction of aromatic rings with sodium and an alcohol in liquid ammonia to form 1,4-cyclohexadienes. The reaction was reported by the Australian chemist Arthur John...
Azidation
Azide is the anion with the formula N3-. It is the conjugate base of hydrazoic acid. Azide is also a functional group in organic chemistry, RN3[1]. N3- is a linear anion that is isoelectronic with CO2...
Acetylene
Acetylene (IUPAC name: ethyne) , C2H2, is a hydrocarbon belonging to the group of alkynes. It is considered to be the simplest of all alkynes as it consists of two hydrogen atoms and two carbon atoms....
Acetylation
Acetylation (or in IUPAC nomenclature ethanoylation) describes a reaction that introduces an acetyl functional group into an organic compound. Deacetylation is the removal of the acetyl group.
Acrylic acid
Acrylic acid or prop-2-enoic acid is a chemical compound (formula C3H4O2) and it is the simplest unsaturated carboxylic acid with a vinyl group at the a-carbon position and a carboxylic acid terminus....
Acyl chloride
In organic chemistry, an acyl chloride (or acid chloride) is an organic compound which is a reactive derivative of a carboxylic acid. As part of its molecular structure, an acyl chloride has the react...
Acetylene
Acetylene (IUPAC name: ethyne) , C2H2, is a hydrocarbon belonging to the group of alkynes. It is considered to be the simplest of all alkynes as it consists of two hydrogen atoms and two carbon atoms....
Acetylation
Acetylation (or in IUPAC nomenclature ethanoylation) describes a reaction that introduces an acetyl functional group into an organic compound. Deacetylation is the removal of the acetyl group.
More Encyclopedia of Custom Chemical Manufacturing >>
 
 Channels
Acetylation Reactions
Acetylenic Chemistry
Acid chlorides
Acrylation
Aldol condensation
Alkoxylation
Alkylation
Allylic bromination
Amidation
Amination
Amino acid synthesis
Ammonolysis
Analytical Testing, Chemical
API Manufacturing,Synthesis
Arylation
Asymmetric synthesis
Azidation
Baeyer-Villiger oxidation
Benzoylation
Biocatalysis, Enzyme Development
Biochemical Manufacturing,Synthesis
Biotransformations
Birch reduction
Blending, Custom Chemical
Bromination Reactions
Butylation
Carbohydrate chemistry
Carbon disulfide chemistry
Carbonylation
Carboxylation
Catalysts, Chemical
Chemical Information, Trade Association
Chiral Synthesis, Catalysts
Chlorination Reactions
Chloromethylation
Chlorosulfonation
Condensation Reactions
Contract Research Services
Coupling Reactions
Cryogenic reactions
Crystallization Control, Chemical
Curtius Rearrangement
Custom Chemical Manufacturing,Synthesis
Cyanation
Cyanide Chemistry
Cyanoethylation
Cyanomethylation
Cyanurations
Cyclization
Cyclopolymerization Reaction
Dehalogenation
Dehydrocyclization
Dehydrogenation
Dehydrohalogenation
Diazotization
Diborane Chemistry
Dieckmann condensation
Diels-Alder reaction
Diketene reactions
Dimethyl sulphate reactions
Distillation Services, Chemical
Doebner-Knoevenagel condensation
Electrochemical reactions
Environmental, Regulatory Support
Epichlorohydrin chemistry
Epoxidation
Equipment, Chemical Process
Esterification
Etherification
Evaporation Tolling, Chemical
Extraction & Purification, Chemical
FDA Regulatory Support
Fermentation Reactions, Chemical
Filtration, Custom Chemical
Fine Chemical Manufacturing
Fluorination Reactions
Formylation
Freeze Drying
Friedel-Crafts Reaction
Fries rearrangement
FTE Chemistry Services
Gabriel synthesis
GeneralInformation
Gomberg-Bachmann reaction
Grignard Reaction
Halide exchange
Halogenation
Heck reaction
Heterocyclic compounds, chemicals
High Potency, Cytotoxic Compounds
High Pressure Reactions
Hofmann rearrangement
Hydrazine chemistry
Hydroformylation
Hydrogen Cyanide reactions
Hydrogen Fluoride reactions
Hydrogenation Reactions
Hydrosilylation
Hydroxylation
IEM Separations
Industrial Chemical Manufacturing
Informex Article
Instrumentation, Chemical Laboratory
Intermediate Chemical Manufacturing
Iodination Reactions
Ionic liquids
Isocyanate Reactions
Japp-Klingemann reaction
Ketalization
Ketene reactions
Leimgruber-Batcho indole synthesis
Liquid ammonia reactions
Liquid Phase Peptide synthesis
Low Temperature Reactions
Mannich reaction
Melt Granulation
Methylation Reactions
Michael addition
Michaelis-Arbuzov reaction
Mitsunobu reaction
Miyaura-Suzuki reaction, coupling
Nanofiltration
Nitration
Nitromethane Chemistry
Nitromethylation
Nitrones
Nitrosation
Olefin Metathesis
Oligonucleotides
Optical resolution
Optically Active Cyanohydrin
Organometallic reactions
Oxidation Reactions, Chemical
Oxidative Coupling
Oxo reactions
Ozonolysis
Peptide Manufacturing Synthesis
Peroxidation
Pharmaceutical Intermediate Manufacturing
Phosgenation
Photochemical reactions
Polycondensation
Polyesterification
Polymerization Reactions
Process Analytical Development
Process Optimization, Chemical
Process Technology, Chemical
Publication Publisher, Chemical
Pyridine Chemicals
Quaternization
Radioisotopic Labeling
REACH Chemical Regulations
Reduction, Catalytic
Reduction, Chemical
Reformatsky reaction
Ring closure
Ritter reaction
Rosenmund reduction
Sandmeyer reaction
Saponification
Scale-up, Custom Chemical
Schiff base reduction
Schotten-Baumann reaction
Separation Solutions, Custom
Sharpless epoxidation
Silylations
Skraup synthesis
Software, Chemistry
Solid Phase Reactions
Sonogashira coupling
Specialty Chemical Manufacturing
Specialty Ketone Reactions
Spray Drying
Steroid Intermediates
Strecker amino acid synthesis
Sulfochlorination
Sulfonation
Sulfoxidation
Swern oxidation
Thiocarbonylation
Thiophosgenation
Toll & Contract Manufacturing
Tosylation
Toxicology, Pharmacology Support
Transamination
Transesterification
Ullmann reaction
Vilsmeier-Haack reaction
Willgerodt rearrangement
Williamson ether synthesis
Wittig reaction
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